The Sonic Hedgehog Pathway Stimulates Prostate Tumor Growth by Paracrine Signaling and Recaptures Embryonic Gene Expression in Tumor Myofibroblasts

The Hedgehog (Hh) pathway contributes to prostate cancer growth and progression. The presence of robust Shh expression in both normal prostate and localized cancer challenged us to explain the unique growth promoting effect in cancer. We show here that paracrine Hh signaling exerts a non-cell autono...

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Detalles Bibliográficos
Autores principales: Shaw, Aubie, Gipp, Jerry, Bushman, Wade
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795794/
https://www.ncbi.nlm.nih.gov/pubmed/19784071
http://dx.doi.org/10.1038/onc.2009.294

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795794/
https://www.ncbi.nlm.nih.gov/pubmed/19784071
http://dx.doi.org/10.1038/onc.2009.294

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