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Application of three-level linear mixed-effects model incorporating gene-age interactions for association analysis of longitudinal family data
Longitudinal studies that collect repeated measurements on the same subjects over time have long been considered as being more powerful and providing much better information on individual changes than cross-sectional data. We propose a three-level linear mixed-effects model for testing genetic main...
Autores principales: | Shi, Gang, Rice, Treva K, Gu, Chi Charles, Rao, Debeeru C |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795992/ https://www.ncbi.nlm.nih.gov/pubmed/20018085 |
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