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Toward the identification of causal genes in complex diseases: a gene-centric joint test of significance combining genomic and transcriptomic data
BACKGROUND: Gene identification using linkage, association, or genome-wide expression is often underpowered. We propose that formal combination of information from multiple gene-identification approaches may lead to the identification of novel loci that are missed when only one form of information i...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795996/ https://www.ncbi.nlm.nih.gov/pubmed/20018089 |