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Integration of gene ontology pathways with North American Rheumatoid Arthritis Consortium genome-wide association data via linear modeling
We describe an empirical Bayesian linear model for integration of functional gene annotation data with genome-wide association data. Using case-control study data from the North American Rheumatoid Arthritis Consortium and gene annotation data from the Gene Ontology, we illustrate how the method can...
Autores principales: | Lebrec, Jérémie JP, Huizinga, Tom WJ, Toes, René EM, Houwing-Duistermaat, Jeanine J, van Houwelingen, Hans C |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795998/ https://www.ncbi.nlm.nih.gov/pubmed/20018091 |
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