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New score tests for age-at-onset linkage analysis in general pedigrees
Our aim is to develop methods for mapping genes related to age at onset in general pedigrees. We propose two score tests, one derived from a gamma frailty model with pairwise likelihood and one derived from a log-normal frailty model with approximated likelihood around the null random effect. The sc...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2796001/ https://www.ncbi.nlm.nih.gov/pubmed/20018094 |