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Induction of Ovarian Leiomyosarcomas in Mice by Conditional Inactivation of Brca1 and p53
BACKGROUND: Approximately one out of every ten cases of epithelial ovarian cancer (EOC) is inherited. The majority of inherited cases of EOC result from mutations in the breast cancer associated gene 1 (BRCA1). In addition to mutation of BRCA1, mutation of the p53 gene is often found in patients wit...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2796165/ https://www.ncbi.nlm.nih.gov/pubmed/20046879 http://dx.doi.org/10.1371/journal.pone.0008404 |