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Exploring Hypotheses of the Actions of TGF-β1 in Epidermal Wound Healing Using a 3D Computational Multiscale Model of the Human Epidermis
In vivo and in vitro studies give a paradoxical picture of the actions of the key regulatory factor TGF-β1 in epidermal wound healing with it stimulating migration of keratinocytes but also inhibiting their proliferation. To try to reconcile these into an easily visualized 3D model of wound healing...
Autores principales: | Sun, Tao, Adra, Salem, Smallwood, Rod, Holcombe, Mike, MacNeil, Sheila |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2796169/ https://www.ncbi.nlm.nih.gov/pubmed/20046881 http://dx.doi.org/10.1371/journal.pone.0008515 |
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