Neopterin: Biomarker of cell-mediated immunity and potent usage as biomarker in silicosis and other occupational diseases

Neopterin is regarded as an early biomarker of the cellular immune response. This low molecular mass compound belongs to the class of pteridine and is a metabolite of guanosine triphosphate, which is produced by the activated macrophages and dendritic cells after stimulation with γ-interferon. An in...

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Detalles Bibliográficos
Autores principales: Pingle, Shubhangi K., Tumane, Rajani G., Jawade, Aruna A.
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2008
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2796748/
https://www.ncbi.nlm.nih.gov/pubmed/20040967
http://dx.doi.org/10.4103/0019-5278.44690
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author Pingle, Shubhangi K.
Tumane, Rajani G.
Jawade, Aruna A.
author_facet Pingle, Shubhangi K.
Tumane, Rajani G.
Jawade, Aruna A.
author_sort Pingle, Shubhangi K.
collection PubMed
description Neopterin is regarded as an early biomarker of the cellular immune response. This low molecular mass compound belongs to the class of pteridine and is a metabolite of guanosine triphosphate, which is produced by the activated macrophages and dendritic cells after stimulation with γ-interferon. An international group acknowledges the fact that the levels of serum neopterin can be used as a marker of the effect of exposure to silica and other occupational diseases. The determination of neopterin is an innovative tool for monitoring diseases associated with the activation of cell-mediated immunity.
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spelling pubmed-27967482009-12-28 Neopterin: Biomarker of cell-mediated immunity and potent usage as biomarker in silicosis and other occupational diseases Pingle, Shubhangi K. Tumane, Rajani G. Jawade, Aruna A. Indian J Occup Environ Med Review Article Neopterin is regarded as an early biomarker of the cellular immune response. This low molecular mass compound belongs to the class of pteridine and is a metabolite of guanosine triphosphate, which is produced by the activated macrophages and dendritic cells after stimulation with γ-interferon. An international group acknowledges the fact that the levels of serum neopterin can be used as a marker of the effect of exposure to silica and other occupational diseases. The determination of neopterin is an innovative tool for monitoring diseases associated with the activation of cell-mediated immunity. Medknow Publications 2008-12 /pmc/articles/PMC2796748/ /pubmed/20040967 http://dx.doi.org/10.4103/0019-5278.44690 Text en © Indian Journal of Occupational and Environmental Medicine http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Pingle, Shubhangi K.
Tumane, Rajani G.
Jawade, Aruna A.
Neopterin: Biomarker of cell-mediated immunity and potent usage as biomarker in silicosis and other occupational diseases
title Neopterin: Biomarker of cell-mediated immunity and potent usage as biomarker in silicosis and other occupational diseases
title_full Neopterin: Biomarker of cell-mediated immunity and potent usage as biomarker in silicosis and other occupational diseases
title_fullStr Neopterin: Biomarker of cell-mediated immunity and potent usage as biomarker in silicosis and other occupational diseases
title_full_unstemmed Neopterin: Biomarker of cell-mediated immunity and potent usage as biomarker in silicosis and other occupational diseases
title_short Neopterin: Biomarker of cell-mediated immunity and potent usage as biomarker in silicosis and other occupational diseases
title_sort neopterin: biomarker of cell-mediated immunity and potent usage as biomarker in silicosis and other occupational diseases
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2796748/
https://www.ncbi.nlm.nih.gov/pubmed/20040967
http://dx.doi.org/10.4103/0019-5278.44690
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AT tumanerajanig neopterinbiomarkerofcellmediatedimmunityandpotentusageasbiomarkerinsilicosisandotheroccupationaldiseases
AT jawadearunaa neopterinbiomarkerofcellmediatedimmunityandpotentusageasbiomarkerinsilicosisandotheroccupationaldiseases

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