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Maternal Infection with Trypanosoma cruzi and Congenital Chagas Disease Induce a Trend to a Type 1 Polarization of Infant Immune Responses to Vaccines

BACKGROUND: We previously showed that newborns congenitally infected with Trypanosoma cruzi (M+B+) display a strong type 1 parasite-specific T cell immune response, whereas uninfected newborns from T. cruzi-infected mothers (M+B−) are prone to produce higher levels of proinflammatory cytokines than...

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Detalles Bibliográficos
Autores principales: Dauby, Nicolas, Alonso-Vega, Cristina, Suarez, Eduardo, Flores, Amilcar, Hermann, Emmanuel, Córdova, Marisol, Tellez, Tatiana, Torrico, Faustino, Truyens, Carine, Carlier, Yves
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2796860/
https://www.ncbi.nlm.nih.gov/pubmed/20041029
http://dx.doi.org/10.1371/journal.pntd.0000571