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Sporadic ALS has compartment-specific aberrant exon splicing and altered cell–matrix adhesion biology

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by progressive weakness from loss of motor neurons. The fundamental pathogenic mechanisms are unknown and recent evidence is implicating a significant role for abnormal exon splicing and RNA processing. Using new...

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Detalles Bibliográficos
Autores principales:	Rabin, Stuart J., Kim, Jae Mun ‘Hugo’, Baughn, Michael, Libby, Ryan T., Kim, Young Joo, Fan, Yuxin, Libby, Randell T., La Spada, Albert, Stone, Brad, Ravits, John
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2010
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2796893/ https://www.ncbi.nlm.nih.gov/pubmed/19864493 http://dx.doi.org/10.1093/hmg/ddp498

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