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Loss of Smyhc1 or Hsp90α1 Function Results in Different Effects on Myofibril Organization in Skeletal Muscles of Zebrafish Embryos
BACKGROUND: Myofibrillogenesis requires the correct folding and assembly of sarcomeric proteins into highly organized sarcomeres. Heat shock protein 90α1 (Hsp90α1) has been implicated as a myosin chaperone that plays a key role in myofibrillogenesis. Knockdown or mutation of hsp90α1 resulted in comp...
Autores principales: | Codina, Marta, Li, Junling, Gutiérrez, Joaquim, Kao, Joseph P. Y., Du, Shao Jun |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797074/ https://www.ncbi.nlm.nih.gov/pubmed/20049323 http://dx.doi.org/10.1371/journal.pone.0008416 |
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