Polymerase-Endonuclease Amplification Reaction (PEAR) for Large-Scale Enzymatic Production of Antisense Oligonucleotides

Antisense oligonucleotides targeting microRNAs or their mRNA targets prove to be powerful tools for molecular biology research and may eventually emerge as new therapeutic agents. Synthetic oligonucleotides are often contaminated with highly homologous failure sequences. Synthesis of a certain oligo...

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Detalles Bibliográficos
Autores principales: Wang, Xiaolong, Gou, Deming, Xu, Shuang-yong
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797076/
https://www.ncbi.nlm.nih.gov/pubmed/20062528
http://dx.doi.org/10.1371/journal.pone.0008430

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797076/
https://www.ncbi.nlm.nih.gov/pubmed/20062528
http://dx.doi.org/10.1371/journal.pone.0008430

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