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The Search for Medications to Treat Stimulant Dependence

Progress in understanding the neurobiology of stimulant dependence has enabled researchers to identify medications whose pharmacological effects suggest that they might help patients initiate abstinence or avoid relapse. Several of these medications and a vaccine have shown encouraging results in co...

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Detalles Bibliográficos
Autor principal: Kampman, Kyle M.
Formato: Texto
Lenguaje:English
Publicado: National Institute on Drug Abuse 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797110/
https://www.ncbi.nlm.nih.gov/pubmed/18497715
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author Kampman, Kyle M.
author_facet Kampman, Kyle M.
author_sort Kampman, Kyle M.
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description Progress in understanding the neurobiology of stimulant dependence has enabled researchers to identify medications whose pharmacological effects suggest that they might help patients initiate abstinence or avoid relapse. Several of these medications and a vaccine have shown encouraging results in controlled clinical trials with cocaine-dependent patients. The search for a medical treatment for methamphetamine dependence started more recently, due to the later emergence of this epidemic, but at least one candidate medication has shown promise in early clinical testing. Treatment approaches that combine efficacious medications and empirically proven behavioral interventions, such as voucher-based reinforcement therapy, will almost certainly produce the best results.
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spelling pubmed-27971102010-01-27 The Search for Medications to Treat Stimulant Dependence Kampman, Kyle M. Addict Sci Clin Pract Research Reviews Progress in understanding the neurobiology of stimulant dependence has enabled researchers to identify medications whose pharmacological effects suggest that they might help patients initiate abstinence or avoid relapse. Several of these medications and a vaccine have shown encouraging results in controlled clinical trials with cocaine-dependent patients. The search for a medical treatment for methamphetamine dependence started more recently, due to the later emergence of this epidemic, but at least one candidate medication has shown promise in early clinical testing. Treatment approaches that combine efficacious medications and empirically proven behavioral interventions, such as voucher-based reinforcement therapy, will almost certainly produce the best results. National Institute on Drug Abuse 2008-06 /pmc/articles/PMC2797110/ /pubmed/18497715 Text en
spellingShingle Research Reviews
Kampman, Kyle M.
The Search for Medications to Treat Stimulant Dependence
title The Search for Medications to Treat Stimulant Dependence
title_full The Search for Medications to Treat Stimulant Dependence
title_fullStr The Search for Medications to Treat Stimulant Dependence
title_full_unstemmed The Search for Medications to Treat Stimulant Dependence
title_short The Search for Medications to Treat Stimulant Dependence
title_sort search for medications to treat stimulant dependence
topic Research Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797110/
https://www.ncbi.nlm.nih.gov/pubmed/18497715
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