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Fibril Fragmentation Enhances Amyloid Cytotoxicity

Fibrils associated with amyloid disease are molecular assemblies of key biological importance, yet how cells respond to the presence of amyloid remains unclear. Cellular responses may not only depend on the chemical composition or molecular properties of the amyloid fibrils, but their physical attri...

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Detalles Bibliográficos
Autores principales:	Xue, Wei-Feng, Hellewell, Andrew L., Gosal, Walraj S., Homans, Steve W., Hewitt, Eric W., Radford, Sheena E.
Formato:	Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2009
Materias:	Protein Structure and Folding
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797196/ https://www.ncbi.nlm.nih.gov/pubmed/19808677 http://dx.doi.org/10.1074/jbc.M109.049809

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