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Dendritic Cell Mediated Delivery of Plasmid DNA Encoding LAMP/HIV-1 Gag Fusion Immunogen Enhances T Cell Epitope Responses in HLA DR4 Transgenic Mice

This report describes the identification and bioinformatics analysis of HLA-DR4-restricted HIV-1 Gag epitope peptides, and the application of dendritic cell mediated immunization of DNA plasmid constructs. BALB/c (H-2d) and HLA-DR4 (DRA1*0101, DRB1*0401) transgenic mice were immunized with immature...

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Detalles Bibliográficos
Autores principales:	Simon, Gregory G., Hu, Yongli, Khan, Asif M., Zhou, Jingshi, Salmon, Jerome, Chikhlikar, Priya R., Jung, Keun-Ok, Marques, Ernesto T. A., August, J. Thomas
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797323/ https://www.ncbi.nlm.nih.gov/pubmed/20052293 http://dx.doi.org/10.1371/journal.pone.0008574

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