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Transglutaminase 2, a Novel Regulator of Eicosanoid Production in Asthma Revealed by Genome-Wide Expression Profiling of Distinct Asthma Phenotypes
BACKGROUND: A frequent manifestation of asthma, exercise-induced bronchoconstriction (EIB), occurs in 30–50% of asthmatics and is characterized by increased release of inflammatory eicosanoids. The objective of this study was to identify genes differentially expressed in EIB and to understand the fu...
Autores principales: | Hallstrand, Teal S., Wurfel, Mark M., Lai, Ying, Ni, Zhanglin, Gelb, Michael H., Altemeier, William A., Beyer, Richard P., Aitken, Moira L., Henderson, William R. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797392/ https://www.ncbi.nlm.nih.gov/pubmed/20052409 http://dx.doi.org/10.1371/journal.pone.0008583 |
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