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Sonic Hedgehog Gene Delivery to the Rodent Heart Promotes Angiogenesis via iNOS/Netrin-1/PKC Pathway

BACKGROUND: We hypothesized that genetic modification of mesenchymal stem cells (MSCs) with Sonic Hedgehog (Shh) transgene, a morphogen during embryonic development and embryonic and adult stem cell growth, improved their survival and angiogenic potential in the ischemic heart via iNOS/netrin/PKC pa...

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Detalles Bibliográficos
Autores principales:	Ahmed, Rafeeq P. H., Haider, Khawaja Husnain, Shujia, Jiang, Afzal, Muhammad Rizwan, Ashraf, Muhammad
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797399/ https://www.ncbi.nlm.nih.gov/pubmed/20052412 http://dx.doi.org/10.1371/journal.pone.0008576

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