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Transforming growth factor-beta inhibits aromatase gene transcription in human trophoblast cells via the Smad2 signaling pathway

BACKGROUND: Transforming growth factor-beta (TGF-beta) is known to exert multiple regulatory functions in the human placenta, including inhibition of estrodial production. We have previously reported that TGF-beta1 decreased aromatase mRNA levels in human trophoblast cells. The objective of this stu...

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Detalles Bibliográficos
Autores principales:	Zhou, Hong, Fu, Guodong, Yu, Hui, Peng, Chun
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797513/ https://www.ncbi.nlm.nih.gov/pubmed/20003198 http://dx.doi.org/10.1186/1477-7827-7-146

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