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Origin of Irreversibility of Cell Cycle Start in Budding Yeast

Budding yeast cells irreversibly commit to a new division cycle at a regulatory transition called Start. This essential decision-making step involves the activation of the SBF/MBF transcription factors. SBF/MBF promote expression of the G1 cyclins encoded by CLN1 and CLN2. Cln1,2 can activate their...

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Detalles Bibliográficos
Autores principales: Charvin, Gilles, Oikonomou, Catherine, Siggia, Eric D., Cross, Frederick R.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797597/
https://www.ncbi.nlm.nih.gov/pubmed/20087409
http://dx.doi.org/10.1371/journal.pbio.1000284