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Origin of Irreversibility of Cell Cycle Start in Budding Yeast
Budding yeast cells irreversibly commit to a new division cycle at a regulatory transition called Start. This essential decision-making step involves the activation of the SBF/MBF transcription factors. SBF/MBF promote expression of the G1 cyclins encoded by CLN1 and CLN2. Cln1,2 can activate their...
Autores principales: | Charvin, Gilles, Oikonomou, Catherine, Siggia, Eric D., Cross, Frederick R. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797597/ https://www.ncbi.nlm.nih.gov/pubmed/20087409 http://dx.doi.org/10.1371/journal.pbio.1000284 |
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