Kidney Development in the Absence of Gdnf and Spry1 Requires Fgf10

GDNF signaling through the Ret receptor tyrosine kinase (RTK) is required for ureteric bud (UB) branching morphogenesis during kidney development in mice and humans. Furthermore, many other mutant genes that cause renal agenesis exert their effects via the GDNF/RET pathway. Therefore, RET signaling...

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Detalles Bibliográficos
Autores principales: Michos, Odyssé, Cebrian, Cristina, Hyink, Deborah, Grieshammer, Uta, Williams, Linda, D'Agati, Vivette, Licht, Jonathan D., Martin, Gail R., Costantini, Frank
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797609/
https://www.ncbi.nlm.nih.gov/pubmed/20084103
http://dx.doi.org/10.1371/journal.pgen.1000809

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