Cargando…

Methylprednisolone inhibits IFN-γ and IL-17 expression and production by cells infiltrating central nervous system in experimental autoimmune encephalomyelitis

BACKGROUND: Glucocorticoids have been shown to be effective in the treatment of autoimmune diseases of the CNS such as multiple sclerosis and its animal model, experimental autoimmune encephalomyelitis (EAE). However, the mechanisms and the site of glucocorticoids' actions are still not complet...

Descripción completa

Detalles Bibliográficos
Autores principales:	Miljković, Željka, Momčilović, Miljana, Miljković, Djordje, Mostarica-Stojković, Marija
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797773/ https://www.ncbi.nlm.nih.gov/pubmed/20003332 http://dx.doi.org/10.1186/1742-2094-6-37

Ejemplares similares

Methylprednisolone inhibits interleukin-17 and interferon-gamma expression by both naive and primed T cells
por: Momčilović, Miljana, et al.
Publicado: (2008)

Gut Microbiota Confers Resistance of Albino Oxford Rats to the Induction of Experimental Autoimmune Encephalomyelitis
por: Stanisavljević, Suzana, et al.
Publicado: (2018)

Correlation of Gut Microbiota Composition with Resistance to Experimental Autoimmune Encephalomyelitis in Rats
por: Stanisavljević, Suzana, et al.
Publicado: (2016)

Oral neonatal antibiotic treatment perturbs gut microbiota and aggravates central nervous system autoimmunity in Dark Agouti rats
por: Stanisavljević, Suzana, et al.
Publicado: (2019)

Phenethyl Ester of Gallic Acid Ameliorates Experimental Autoimmune Encephalomyelitis
por: Stegnjaić, Goran, et al.
Publicado: (2022)

IFN-γ protects from lethal IL-17 mediated viral encephalomyelitis independent of neutrophils
por: Savarin, Carine, et al.
Publicado: (2012)

Astrocyte response to IFN-γ limits IL-6-mediated microglia activation and progressive autoimmune encephalomyelitis
por: Savarin, Carine, et al.
Publicado: (2015)

Preventive Treatment with Methylprednisolone Paradoxically Exacerbates Experimental Autoimmune Encephalomyelitis
por: Wüst, Simone, et al.
Publicado: (2012)

GRIM-19 Ameliorates Multiple Sclerosis in a Mouse Model of Experimental Autoimmune Encephalomyelitis with Reciprocal Regulation of IFNγ/Th1 and IL-17A/Th17 Cells
por: Moon, Jeonghyeon, et al.
Publicado: (2020)

Innate IFN-γ ameliorates experimental autoimmune encephalomyelitis and promotes myeloid expansion and PDL-1 expression
por: White, Madeleine P. J., et al.
Publicado: (2018)

Pentoxifylline Prevents Autoimmune Mediated Inflammation in Low Dose Streptozotocin Induced Diabetes
por: Stošić-Grujičić, Stanislava D., et al.
Publicado: (2001)

IFN-γ– and IL-10–expressing virus epitope-specific Foxp3(+) T reg cells in the central nervous system during encephalomyelitis
por: Zhao, Jingxian, et al.
Publicado: (2011)

Sustained TNF production by central nervous system infiltrating macrophages promotes progressive autoimmune encephalomyelitis
por: Valentin-Torres, Alice, et al.
Publicado: (2016)

Bidirectional Effect of IFN-γ on Th17 Responses in Experimental Autoimmune Uveitis
por: Shao, Hui, et al.
Publicado: (2022)

Lithium Controls Central Nervous System Autoimmunity through Modulation of IFN-γ Signaling
por: Rowse, Amber L., et al.
Publicado: (2012)

Inhibition of Myeloid Differentiation Factor 88 Reduces Human and Mouse T-Cell Interleukin-17 and IFNγ Production and Ameliorates Experimental Autoimmune Encephalomyelitis Induced in Mice
por: Dishon, Shira, et al.
Publicado: (2017)

The H(2)S Donor GYY4137 Stimulates Reactive Oxygen Species Generation in BV2 Cells While Suppressing the Secretion of TNF and Nitric Oxide
por: Lazarević, Milica, et al.
Publicado: (2018)

Upregulation of Tolerogenic Pathways by the Hydrogen Sulfide Donor GYY4137 and Impaired Expression of H(2)S-Producing Enzymes in Multiple Sclerosis
por: Lazarević, Milica, et al.
Publicado: (2020)

Sinomenine reduces iNOS expression via inhibiting the T-bet IFN-γ pathway in experimental autoimmune encephalomyelitis in rats
por: Gu, Bingjie, et al.
Publicado: (2012)

IFN-gamma signaling in the central nervous system controls the course of experimental autoimmune encephalomyelitis independently of the localization and composition of inflammatory foci
por: Lee, Eunyoung, et al.
Publicado: (2012)

Restrained Th17 response and myeloid cell infiltration into the central nervous system by human decidua-derived mesenchymal stem cells during experimental autoimmune encephalomyelitis
por: Bravo, Beatriz, et al.
Publicado: (2016)

Anti-inflammatory mechanisms of IFN-γ studied in experimental autoimmune encephalomyelitis reveal neutrophils as a potential target in multiple sclerosis
por: Miller, Nichole M., et al.
Publicado: (2015)

Ingested (Oral) Adrenocorticotropic Hormone Inhibits IL-17 in the Central Nervous System in the Mouse Model of Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis
por: Dittel, Landon J., et al.
Publicado: (2022)

Erratum to: IFN-gamma signaling in the central nervous system controls the course of experimental autoimmune encephalomyelitis independently of the localization and composition of inflammatory foci
por: Lee, Eunyoung, et al.
Publicado: (2016)

Functional interleukin-17 receptor A is expressed in central nervous system glia and upregulated in experimental autoimmune encephalomyelitis
por: Sarma, Jayasri Das, et al.
Publicado: (2009)

Dynamics of Intraocular IFN-γ, IL-17 and IL-10-Producing Cell Populations during Relapsing and Monophasic Rat Experimental Autoimmune Uveitis
por: Kaufmann, Ulrike, et al.
Publicado: (2012)

Alcohol dependence promotes systemic IFN-γ and IL-17 responses in mice
por: Frank, Kayla, et al.
Publicado: (2020)

Parthenolide Suppresses T Helper 17 and Alleviates Experimental Autoimmune Encephalomyelitis
por: Zhang, Zhihui, et al.
Publicado: (2022)

Splitting the “Unsplittable”: Dissecting Resident and Infiltrating Macrophages in Experimental Autoimmune Encephalomyelitis
por: Koeniger, Tobias, et al.
Publicado: (2017)

Clozapine reduces infiltration into the CNS by targeting migration in experimental autoimmune encephalomyelitis
por: Robichon, Katharina, et al.
Publicado: (2020)

IFN‐γ(+)IL‐17(+)Th17 cells regulate fibrosis through secreting IL‐21 in systemic scleroderma
por: Xing, Xiaojing, et al.
Publicado: (2020)

CD4 T-cell expression of IFN-γ and IL-17 in pediatric malarial anemia
por: Raballah, Evans, et al.
Publicado: (2017)

Ethyl pyruvate, a versatile protector in inflammation and autoimmunity
por: Koprivica, Ivan, et al.
Publicado: (2022)

A crucial role for interleukin (IL)-1 in the induction of IL-17–producing T cells that mediate autoimmune encephalomyelitis
por: Sutton, Caroline, et al.
Publicado: (2006)

Neutralization of Interleukin-9 Decreasing Mast Cells Infiltration in Experimental Autoimmune Encephalomyelitis
por: Yin, Jun-Jie, et al.
Publicado: (2017)

Neurons promote encephalitogenic CD4(+) lymphocyte infiltration in experimental autoimmune encephalomyelitis
por: Nakazato, Yuki, et al.
Publicado: (2020)

BAFF Promotes Th17 Cells and Aggravates Experimental Autoimmune Encephalomyelitis
por: Zhou, Xiaohui, et al.
Publicado: (2011)

HVEM Promotes the Osteogenesis of allo-MSCs by Inhibiting the Secretion of IL-17 and IFN-γ in Vγ4T Cells
por: He, Lei, et al.
Publicado: (2021)

Elevated serum IFN-γand IFN-γ/IL-6 ratio in Kikuchi-Fujimoto disease
por: He, Tingyan, et al.
Publicado: (2023)

Inflamm-Aging-Related Cytokines of IL-17 and IFN-γ Accelerate Osteoclastogenesis and Periodontal Destruction
por: Tan, Jingyi, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_grdmkaj7r9cvrcio2pgp1e38uo