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Genes flanking Xist in mouse and human are separated on the X chromosome in American marsupials
X inactivation, the transcriptional silencing of one of the two X chromosomes in female mammals, achieves dosage compensation of X-linked genes relative to XY males. In eutherian mammals X inactivation is regulated by the X-inactive specific transcript (Xist), a cis-acting non-coding RNA that trigge...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797855/ https://www.ncbi.nlm.nih.gov/pubmed/17333537 http://dx.doi.org/10.1007/s10577-006-1115-9 |