Gestational Diabetes Mellitus Resulting From Impaired β-Cell Compensation in the Absence of FoxM1, a Novel Downstream Effector of Placental Lactogen

OBJECTIVE: The objectives of the study were to determine whether the cell cycle transcription factor, FoxM1, is required for glucose homeostasis and β-cell mass expansion in maternal islets during pregnancy and whether FoxM1 is essential for placental lactogen (PL)-induced β-cell proliferation. RESE...

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Detalles Bibliográficos
Autores principales: Zhang, Hongjie, Zhang, Jia, Pope, Christine F., Crawford, Laura A., Vasavada, Rupangi C., Jagasia, Shubhada M., Gannon, Maureen
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797915/
https://www.ncbi.nlm.nih.gov/pubmed/19833884
http://dx.doi.org/10.2337/db09-0050

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