Cargando…

Experimental Endotoxemia Induces Adipose Inflammation and Insulin Resistance in Humans

OBJECTIVE: An emerging model of metabolic syndrome and type 2 diabetes is of adipose dysfunction with leukocyte recruitment into adipose leading to chronic inflammation and insulin resistance (IR). This study sought to explore potential mechanisms of inflammatory-induced IR in humans with a focus on...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mehta, Nehal N., McGillicuddy, Fiona C., Anderson, Paul D., Hinkle, Christine C., Shah, Rachana, Pruscino, Leticia, Tabita-Martinez, Jennifer, Sellers, Kim F., Rickels, Michael R., Reilly, Muredach P.
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2010
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797919/ https://www.ncbi.nlm.nih.gov/pubmed/19794059 http://dx.doi.org/10.2337/db09-0367

Ejemplares similares

Gene Profiling of Human Adipose Tissue During Evoked Inflammation In Vivo
por: Shah, Rachana, et al.
Publicado: (2009)

Peroxisome Proliferator–Activated Receptor-α Agonism With Fenofibrate Does Not Suppress Inflammatory Responses to Evoked Endotoxemia
por: Mulvey, Claire K., et al.
Publicado: (2012)

A human model of inflammatory cardio-metabolic dysfunction; a double blind placebo-controlled crossover trial
por: Mehta, Nehal N, et al.
Publicado: (2012)

Macrophage Migration Inhibitory Factor Deficiency Ameliorates High-Fat Diet Induced Insulin Resistance in Mice with Reduced Adipose Inflammation and Hepatic Steatosis
por: Finucane, Orla M., et al.
Publicado: (2014)

Differential Associations of Oral Glucose Tolerance Test–Derived Measures of Insulin Sensitivity and Pancreatic β-Cell Function With Coronary Artery Calcification and Microalbuminuria in Type 2 Diabetes
por: Mulvey, Claire K., et al.
Publicado: (2014)

Fractalkine Is a Novel Human Adipochemokine Associated With Type 2 Diabetes
por: Shah, Rachana, et al.
Publicado: (2011)

Nutritionally Derived Metabolic Cues Typical of the Obese Microenvironment Increase Cholesterol Efflux Capacity of Adipose Tissue Macrophages
por: O'Reilly, Marcella E., et al.
Publicado: (2018)

Expression of Calgranulin Genes S100A8, S100A9 and S100A12 Is Modulated by n-3 PUFA during Inflammation in Adipose Tissue and Mononuclear Cells
por: Shah, Rachana D., et al.
Publicado: (2017)

Lack of Interleukin-1 Receptor I (IL-1RI) Protects Mice From High-Fat Diet–Induced Adipose Tissue Inflammation Coincident With Improved Glucose Homeostasis
por: McGillicuddy, Fiona C., et al.
Publicado: (2011)

Race and gender variation in response to evoked inflammation
por: Ferguson, Jane F, et al.
Publicado: (2013)

Unravelling HDL—Looking beyond the Cholesterol Surface to the Quality Within
por: Kajani, Sarina, et al.
Publicado: (2018)

Palmitic Acid and Oleic Acid Differently Modulate TLR2-Mediated Inflammatory Responses in Microglia and Macrophages
por: Howe, Anne-Marie, et al.
Publicado: (2022)

Sodium salicylate rewires hepatic metabolic pathways in obesity and attenuates IL-1β secretion from adipose tissue: The implications for obesity-impaired reverse cholesterol transport
por: Kajani, Sarina, et al.
Publicado: (2021)

The Effect of Hyperventilation Syndrome on Ionized and Serum Calcium: A Case Presentation in the Emergency Department
por: McGillicuddy, Casey, et al.
Publicado: (2023)

Targeting adipose tissue via systemic gene therapy
por: O'Neill, Sean M., et al.
Publicado: (2014)

Metabolic Effects of CX3CR1 Deficiency in Diet-Induced Obese Mice
por: Shah, Rachana, et al.
Publicado: (2015)

A Proteomics-Based Assessment of Inflammation Signatures in Endotoxemia
por: Burnap, Sean A., et al.
Publicado: (2021)

Endotoxemia-induced inflammation and the effect on the human brain
por: van den Boogaard, Mark, et al.
Publicado: (2010)

Effect of Rifaximin Treatment on Endotoxemia and Insulin Sensitivity in Humans
por: Finlin, Brian S, et al.
Publicado: (2019)

Yogurt Supplementation Attenuated Insulin Resistance in Obese Mice by Reducing Systemic Markers of Metabolic Endotoxemia and Inflammation
por: Hasegawa, Yu, et al.
Publicado: (2022)

Role of nitric oxide in inflammation and tissue injury during endotoxemia and hemorrhagic shock.
por: Shah, N S, et al.
Publicado: (1998)

Appendiceal neoplasms and histological involvement of the mesoappendix: A case series
por: Rait, Jaideep Singh, et al.
Publicado: (2020)

Bow hunter syndrome
por: Kühn, Anna Luisa, et al.
Publicado: (2022)

Insuffisance vertébrobasilaire
por: Kühn, Anna Luisa, et al.
Publicado: (2023)

Disassociation of Muscle Insulin Signaling and Insulin-Stimulated Glucose Uptake during Endotoxemia
por: Mulligan, Kimberly X., et al.
Publicado: (2012)

Endotoxemia by Porphyromonas gingivalis Alters Endocrine Functions in Brown Adipose Tissue
por: Hatasa, Masahiro, et al.
Publicado: (2021)

A Quantitative Assessment of the Role of the Parasite Amoebophrya in the Termination of Alexandrium fundyense Blooms within a Small Coastal Embayment
por: Velo-Suárez, Lourdes, et al.
Publicado: (2013)

Role of Metabolic Endotoxemia in Systemic Inflammation and Potential Interventions
por: Mohammad, Shireen, et al.
Publicado: (2021)

Liraglutide dictates macrophage phenotype in apolipoprotein E null mice during early atherosclerosis
por: Bruen, Robyn, et al.
Publicado: (2017)

71 Burn Intensive Care Unit Early Mobility Competency Based Orientation
por: McGillicuddy, Jennie, et al.
Publicado: (2022)

Long-term exposure to a high-fat diet results in the development of glucose intolerance and insulin resistance in interleukin-1 receptor I-deficient mice
por: McGillicuddy, Fiona C., et al.
Publicado: (2013)

Synergistic Modulation of Inflammatory but not Metabolic Effects of High-Fat Feeding by CCR2 and CX3CR1
por: Zhang, Hanrui, et al.
Publicado: (2017)

Mechanical ventilation worsens abdominal edema and inflammation in porcine endotoxemia
por: Lattuada, Marco, et al.
Publicado: (2013)

Precision nutrition for targeting pathophysiology of cardiometabolic phenotypes
por: Shannon, Christopher E., et al.
Publicado: (2023)

Dynamics of an intense Alexandrium catenella red tide in the Gulf of Maine: satellite observations and numerical modeling
por: Li, Yizhen, et al.
Publicado: (2020)

Latent Inflammation and Insulin Resistance in Adipose Tissue
por: Stafeev, I. S., et al.
Publicado: (2017)

Inflammation and Vascular Remodeling
por: Aihara, Ken-ichi, et al.
Publicado: (2012)

Endotoxemia-mediated activation of acetyltransferase P300 impairs insulin signaling in obesity
por: Cao, Jia, et al.
Publicado: (2017)

Is a postintubation chest radiograph necessary in the emergency department?
por: McGillicuddy, Daniel C., et al.
Publicado: (2009)

Stress Induces Endotoxemia and Low-Grade Inflammation by Increasing Barrier Permeability
por: de Punder, Karin, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_2blp0pk466aftmqvatkpou30bq