Nephrin Is Expressed on the Surface of Insulin Vesicles and Facilitates Glucose-Stimulated Insulin Release

OBJECTIVE: Nephrin, an immunoglobulin-like protein essential for the function of the glomerular podocyte and regulated in diabetic nephropathy, is also expressed in pancreatic β-cells, where its function remains unknown. The aim of this study was to investigate whether diabetes modulates nephrin exp...

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Detalles Bibliográficos
Autores principales: Fornoni, Alessia, Jeon, Jongmin, Varona Santos, Javier, Cobianchi, Lorenzo, Jauregui, Alexandra, Inverardi, Luca, Mandic, Slavena A., Bark, Christina, Johnson, Kevin, McNamara, George, Pileggi, Antonello, Molano, R. Damaris, Reiser, Jochen, Tryggvason, Karl, Kerjaschki, Dontscho, Berggren, Per-Olof, Mundel, Peter, Ricordi, Camillo
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797921/
https://www.ncbi.nlm.nih.gov/pubmed/19833886
http://dx.doi.org/10.2337/db09-0655

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