High-Throughput Assay for Modulators of Mitochondrial Membrane Potential Identifies a Novel Compound With Beneficial Effects on db/db Mice

OBJECTIVE: Recently, several drugs have been shown to exert beneficial effects for metabolic syndrome through mild regulation of mitochondrial function. Hence, we explored a strategy of targeting mitochondrial function to improve glucose and lipid metabolism. RESEARCH DESIGN AND METHODS: Mitochondri...

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Detalles Bibliográficos
Autores principales: Qiu, Bei-Ying, Turner, Nigel, Li, Yuan-Yuan, Gu, Min, Huang, Meng-Wei, Wu, Fang, Pang, Tao, Nan, Fa-Jun, Ye, Ji-Ming, Li, Jing-Ya, Li, Jia
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797930/
https://www.ncbi.nlm.nih.gov/pubmed/19833880
http://dx.doi.org/10.2337/db09-0223

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