Cargando…
Idd9.1 Locus Controls the Suppressive Activity of FoxP3(+)CD4(+)CD25(+) Regulatory T-Cells
OBJECTIVE: The ∼45-cM insulin-dependent diabetes 9 (Idd9) region on mouse chromosome 4 harbors several different type 1 diabetes–associated loci. Nonobese diabetic (NOD) mice congenic for the Idd9 region of C57BL/10 (B10) mice, carrying antidiabetogenic alleles in three different Idd9 subregions (Id...
Autores principales: | Yamanouchi, Jun, Puertas, Maria-Carmen, Verdaguer, Joan, Lyons, Paul A., Rainbow, Daniel B., Chamberlain, Giselle, Hunter, Kara M., Peterson, Laurence B., Wicker, Linda S., Santamaria, Pere |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797933/ https://www.ncbi.nlm.nih.gov/pubmed/19833887 http://dx.doi.org/10.2337/db09-0648 |
Ejemplares similares
-
Fine mapping of type 1 diabetes regions Idd9.1 and Idd9.2 reveals genetic complexity
por: Hamilton-Williams, Emma E., et al.
Publicado: (2013) -
Idd9.2 and Idd9.3 Protective Alleles Function in CD4(+) T-Cells and Nonlymphoid Cells to Prevent Expansion of Pathogenic Islet-Specific CD8(+) T-Cells
por: Hamilton-Williams, Emma E., et al.
Publicado: (2010) -
Cellular Mechanisms of Restored β-Cell Tolerance Mediated by Protective Alleles of Idd3 and Idd5
por: Hamilton-Williams, Emma E., et al.
Publicado: (2012) -
CD4(+)CD25(high)FoxP3(+) Regulatory T-cells in Hematologic Diseases
por: Moon, Hee-Won, et al.
Publicado: (2011) -
Idd9/11 Genetic Locus Regulates Diabetogenic Activity of CD4 T-Cells in Nonobese Diabetic (NOD) Mice
por: Chen, Yi-Guang, et al.
Publicado: (2008)