Gene Variants in the Novel Type 2 Diabetes Loci CDC123/CAMK1D, THADA, ADAMTS9, BCL11A, and MTNR1B Affect Different Aspects of Pancreatic β-Cell Function

OBJECTIVE: Recently, results from a meta-analysis of genome-wide association studies have yielded a number of novel type 2 diabetes loci. However, conflicting results have been published regarding their effects on insulin secretion and insulin sensitivity. In this study we used hyperglycemic clamps...

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Detalles Bibliográficos
Autores principales: Simonis-Bik, Annemarie M., Nijpels, Giel, van Haeften, Timon W., Houwing-Duistermaat, Jeanine J., Boomsma, Dorret I., Reiling, Erwin, van Hove, Els C., Diamant, Michaela, Kramer, Mark H.H., Heine, Robert J., Maassen, J. Antonie, Slagboom, P. Eline, Willemsen, Gonneke, Dekker, Jacqueline M., Eekhoff, Elisabeth M., de Geus, Eco J., 't Hart, Leen M.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797936/
https://www.ncbi.nlm.nih.gov/pubmed/19833888
http://dx.doi.org/10.2337/db09-1048

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