Insulin Resistance Is Associated With Higher Intramyocellular Triglycerides in Type I but Not Type II Myocytes Concomitant With Higher Ceramide Content

OBJECTIVE: We tested the primary hypotheses that sphingolipid and diacylglycerol (DAG) content is higher within insulin-resistant muscle and that the association between intramyocellular triglycerides (IMTG) and insulin resistance is muscle fiber type specific. RESEARCH DESIGN AND METHODS: A nested...

Descripción completa

Detalles Bibliográficos
Autores principales: Coen, Paul M., Dubé, John J., Amati, Francesca, Stefanovic-Racic, Maja, Ferrell, Robert E., Toledo, Frederico G.S., Goodpaster, Bret H.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797948/
https://www.ncbi.nlm.nih.gov/pubmed/19833891
http://dx.doi.org/10.2337/db09-0988

Ejemplares similares

Ejemplares similares