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P19 H-Ras Induces G1/S Phase Delay Maintaining Cells in a Reversible Quiescence State

BACKGROUND: Three functional c-ras genes, known as c-H-ras, c-K-ras, and c-N-ras, have been largely studied in mammalian cells with important insights into normal and tumorigenic cellular signal transduction events. Two K-Ras mRNAs are obtained from the same pre-mRNA by alternative splicing. H-Ras p...

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Detalles Bibliográficos
Autores principales: Camats, Maria, Kokolo, Mariette, Heesom, Kate J., Ladomery, Michael, Bach-Elias, Montse
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2798614/
https://www.ncbi.nlm.nih.gov/pubmed/20046837
http://dx.doi.org/10.1371/journal.pone.0008513