Understanding and Targeting the Eukaryotic Translation Initiation Factor eIF4E in Head and Neck Cancer

The eukaryotic translation initiation factor eIF4E is elevated in about 30% of human malignancies including HNSCC where its levels correlate with poor prognosis. Here, we discuss the biochemical and molecular underpinnings of the oncogenic potential of eIF4E. Studies in human leukemia specimens, and...

Descripción completa

Detalles Bibliográficos
Autores principales: Culjkovic, Biljana, Borden, Katherine L.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2009
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2798714/
https://www.ncbi.nlm.nih.gov/pubmed/20049173
http://dx.doi.org/10.1155/2009/981679

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2798714/
https://www.ncbi.nlm.nih.gov/pubmed/20049173
http://dx.doi.org/10.1155/2009/981679

Ejemplares similares