Cargando…

Ciliary Neurotrophic Factor Protects Striatal Neurons against Excitotoxicity by Enhancing Glial Glutamate Uptake

Ciliary neurotrophic factor (CNTF) is a potent neuroprotective cytokine in different animal models of glutamate-induced excitotoxicity, although its action mechanisms are still poorly characterized. We tested the hypothesis that an increased function of glial glutamate transporters (GTs) could under...

Descripción completa

Detalles Bibliográficos
Autores principales: Beurrier, Corinne, Faideau, Mathilde, Bennouar, Khaled-Ezaheir, Escartin, Carole, Kerkerian-Le Goff, Lydia, Bonvento, Gilles, Gubellini, Paolo
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2798716/
https://www.ncbi.nlm.nih.gov/pubmed/20062544
http://dx.doi.org/10.1371/journal.pone.0008550