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Conformational effects of a common codon 751 polymorphism on the C-terminal domain of the xeroderma pigmentosum D protein

AIM: The xeroderma pigmentosum D (XPD) protein is a DNA helicase involved in the repair of DNA damage, including nucleotide excision repair (NER) and transcription-coupled repair (TCR). The C-terminal domain of XPD has been implicated in interactions with other components of the TFIIH complex, and i...

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Detalles Bibliográficos
Autores principales: Monaco, Regina, Rosal, Ramon, Dolan, Michael A., Pincus, Matthew R., Freyer, Greg, Brandt-Rauf, Paul W.
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2799167/
https://www.ncbi.nlm.nih.gov/pubmed/19661678
http://dx.doi.org/10.4103/1477-3163.54918