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Promoter methylation of IGFBP-3 and p53 expression in ovarian endometrioid carcinoma
BACKGROUND: Insulin-like growth factor binding protein (IGFBP-3) is an antiproliferative, pro-apoptotic and invasion suppressor protein which is transcriptionally regulated by p53. Promoter methylation has been linked to gene silencing and cancer progression. We studied the correlation between IGFBP...
Autores principales: | Torng, Pao-Ling, Lin, Ching-Wei, Chan, Michael WY, Yang, Hui-Wen, Huang, Su-Cheng, Lin, Chin-Tarng |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2799391/ https://www.ncbi.nlm.nih.gov/pubmed/20003326 http://dx.doi.org/10.1186/1476-4598-8-120 |
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