Cargando…

DNA microarray profiling of genes differentially regulated by the histone deacetylase inhibitors vorinostat and LBH589 in colon cancer cell lines

BACKGROUND: Despite the significant progress made in colon cancer chemotherapy, advanced disease remains largely incurable and novel efficacious chemotherapies are urgently needed. Histone deacetylase inhibitors (HDACi) represent a novel class of agents which have demonstrated promising preclinical...

Descripción completa

Detalles Bibliográficos
Autores principales: LaBonte, Melissa J, Wilson, Peter M, Fazzone, William, Groshen, Susan, Lenz, Heinz-Josef, Ladner, Robert D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2799439/
https://www.ncbi.nlm.nih.gov/pubmed/19948057
http://dx.doi.org/10.1186/1755-8794-2-67