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DNA microarray profiling of genes differentially regulated by the histone deacetylase inhibitors vorinostat and LBH589 in colon cancer cell lines
BACKGROUND: Despite the significant progress made in colon cancer chemotherapy, advanced disease remains largely incurable and novel efficacious chemotherapies are urgently needed. Histone deacetylase inhibitors (HDACi) represent a novel class of agents which have demonstrated promising preclinical...
Autores principales: | LaBonte, Melissa J, Wilson, Peter M, Fazzone, William, Groshen, Susan, Lenz, Heinz-Josef, Ladner, Robert D |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2799439/ https://www.ncbi.nlm.nih.gov/pubmed/19948057 http://dx.doi.org/10.1186/1755-8794-2-67 |
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