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Toxicology in the Fast Lane: Application of High-Throughput Bioassays to Detect Modulation of Key Enzymes and Receptors

BACKGROUND: Legislation at state, federal, and international levels is requiring rapid evaluation of the toxicity of numerous chemicals. Whole-animal toxicologic studies cannot yield the necessary throughput in a cost-effective fashion, leading to a critical need for a faster and more cost-effective...

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Detalles Bibliográficos
Autores principales: Morisseau, Christophe, Merzlikin, Oleg, Lin, Amy, He, Guochun, Feng, Wei, Padilla, Isela, Denison, Michael S., Pessah, Isaac N., Hammock, Bruce D.
Formato: Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2799460/
https://www.ncbi.nlm.nih.gov/pubmed/20049205
http://dx.doi.org/10.1289/ehp.0900834