Marburg Virus Evades Interferon Responses by a Mechanism Distinct from Ebola Virus

Previous studies have demonstrated that Marburg viruses (MARV) and Ebola viruses (EBOV) inhibit interferon (IFN)-α/β signaling but utilize different mechanisms. EBOV inhibits IFN signaling via its VP24 protein which blocks the nuclear accumulation of tyrosine phosphorylated STAT1. In contrast, MARV...

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Detalles Bibliográficos
Autores principales: Valmas, Charalampos, Grosch, Melanie N., Schümann, Michael, Olejnik, Judith, Martinez, Osvaldo, Best, Sonja M., Krähling, Verena, Basler, Christopher F., Mühlberger, Elke
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2799553/
https://www.ncbi.nlm.nih.gov/pubmed/20084112
http://dx.doi.org/10.1371/journal.ppat.1000721

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2799553/
https://www.ncbi.nlm.nih.gov/pubmed/20084112
http://dx.doi.org/10.1371/journal.ppat.1000721

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