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High-Resolution Diffusion Tensor MR Imaging for Evaluating Myocardial Anisotropy and Fiber Tracking at 3T: the Effect of the Number of Diffusion-Sensitizing Gradient Directions

OBJECTIVE: We wanted to evaluate the effect of the number of diffusion-sensitizing gradient directions on the image quality for evaluating myocardial anisotropy and fiber tracking by using in vitro diffusion tensor MR imaging (DT-MRI). MATERIALS AND METHODS: The DT-MR images, using a SENSE-based ech...

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Autores principales: Choi, Sang Il, Kang, Joon-Won, Chun, Eun Ju, Choi, Seong Hoon, Lim, Tae-Hwan
Formato: Texto
Lenguaje:English
Publicado: The Korean Society of Radiology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2799651/
https://www.ncbi.nlm.nih.gov/pubmed/20046495
http://dx.doi.org/10.3348/kjr.2010.11.1.54
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author Choi, Sang Il
Kang, Joon-Won
Chun, Eun Ju
Choi, Seong Hoon
Lim, Tae-Hwan
author_facet Choi, Sang Il
Kang, Joon-Won
Chun, Eun Ju
Choi, Seong Hoon
Lim, Tae-Hwan
author_sort Choi, Sang Il
collection PubMed
description OBJECTIVE: We wanted to evaluate the effect of the number of diffusion-sensitizing gradient directions on the image quality for evaluating myocardial anisotropy and fiber tracking by using in vitro diffusion tensor MR imaging (DT-MRI). MATERIALS AND METHODS: The DT-MR images, using a SENSE-based echoplanar imaging technique, were acquired from ten excised porcine hearts by using a 3T MR scanner. With a b-value of 800 s/mm(2), the diffusion tensor images were obtained for 6, 15 and 32 diffusion-sensitizing gradient directions at the midventricular level. The number of tracked fibers, the fractional anisotropy (FA), and the length of the tracked fibers were measured for the quantitative analysis. Two radiologists assessed the image quality of the fiber tractography for the qualitative analysis. RESULTS: By increasing the number of diffusion-sensitizing gradient directions from 6 to 15, and then to 32, the FA and standard deviation were significantly reduced (p < 0.01), and the number of tracked fibers and the length of the tracked fibers were significantly increased (p < 0.01). The image quality of the fiber tractography was significantly increased with the increased number of diffusion-sensitizing gradient directions (p < 0.01). CONCLUSION: The image quality of in vitro DT-MRI is significantly improved as the number of diffusion-sensitizing gradient directions is increased.
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spelling pubmed-27996512010-01-01 High-Resolution Diffusion Tensor MR Imaging for Evaluating Myocardial Anisotropy and Fiber Tracking at 3T: the Effect of the Number of Diffusion-Sensitizing Gradient Directions Choi, Sang Il Kang, Joon-Won Chun, Eun Ju Choi, Seong Hoon Lim, Tae-Hwan Korean J Radiol Original Article OBJECTIVE: We wanted to evaluate the effect of the number of diffusion-sensitizing gradient directions on the image quality for evaluating myocardial anisotropy and fiber tracking by using in vitro diffusion tensor MR imaging (DT-MRI). MATERIALS AND METHODS: The DT-MR images, using a SENSE-based echoplanar imaging technique, were acquired from ten excised porcine hearts by using a 3T MR scanner. With a b-value of 800 s/mm(2), the diffusion tensor images were obtained for 6, 15 and 32 diffusion-sensitizing gradient directions at the midventricular level. The number of tracked fibers, the fractional anisotropy (FA), and the length of the tracked fibers were measured for the quantitative analysis. Two radiologists assessed the image quality of the fiber tractography for the qualitative analysis. RESULTS: By increasing the number of diffusion-sensitizing gradient directions from 6 to 15, and then to 32, the FA and standard deviation were significantly reduced (p < 0.01), and the number of tracked fibers and the length of the tracked fibers were significantly increased (p < 0.01). The image quality of the fiber tractography was significantly increased with the increased number of diffusion-sensitizing gradient directions (p < 0.01). CONCLUSION: The image quality of in vitro DT-MRI is significantly improved as the number of diffusion-sensitizing gradient directions is increased. The Korean Society of Radiology 2010 2009-12-28 /pmc/articles/PMC2799651/ /pubmed/20046495 http://dx.doi.org/10.3348/kjr.2010.11.1.54 Text en Copyright © 2010 The Korean Society of Radiology http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Choi, Sang Il
Kang, Joon-Won
Chun, Eun Ju
Choi, Seong Hoon
Lim, Tae-Hwan
High-Resolution Diffusion Tensor MR Imaging for Evaluating Myocardial Anisotropy and Fiber Tracking at 3T: the Effect of the Number of Diffusion-Sensitizing Gradient Directions
title High-Resolution Diffusion Tensor MR Imaging for Evaluating Myocardial Anisotropy and Fiber Tracking at 3T: the Effect of the Number of Diffusion-Sensitizing Gradient Directions
title_full High-Resolution Diffusion Tensor MR Imaging for Evaluating Myocardial Anisotropy and Fiber Tracking at 3T: the Effect of the Number of Diffusion-Sensitizing Gradient Directions
title_fullStr High-Resolution Diffusion Tensor MR Imaging for Evaluating Myocardial Anisotropy and Fiber Tracking at 3T: the Effect of the Number of Diffusion-Sensitizing Gradient Directions
title_full_unstemmed High-Resolution Diffusion Tensor MR Imaging for Evaluating Myocardial Anisotropy and Fiber Tracking at 3T: the Effect of the Number of Diffusion-Sensitizing Gradient Directions
title_short High-Resolution Diffusion Tensor MR Imaging for Evaluating Myocardial Anisotropy and Fiber Tracking at 3T: the Effect of the Number of Diffusion-Sensitizing Gradient Directions
title_sort high-resolution diffusion tensor mr imaging for evaluating myocardial anisotropy and fiber tracking at 3t: the effect of the number of diffusion-sensitizing gradient directions
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2799651/
https://www.ncbi.nlm.nih.gov/pubmed/20046495
http://dx.doi.org/10.3348/kjr.2010.11.1.54
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