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Effect of Sildenafil on Neuropathic Pain and Hemodynamics in Rats

PURPOSE: The inhibition of phosphodiesterase 5 produces an antinociception through the increase of cyclic guanosine monophosphate (cGMP), and increasing cGMP levels enhance the release of γ-aminobutyric acid (GABA). Furthermore, this phosphodiesterase 5 plays a pivotal role in the regulation of the...

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Detalles Bibliográficos
Autores principales:	Huang, Lan Ji, Yoon, Myung Ha, Choi, Jeong Il, Kim, Woong Mo, Lee, Hyung Gon, Kim, Yeo Ok
Formato:	Texto
Lenguaje:	English
Publicado:	Yonsei University College of Medicine 2010
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2799976/ https://www.ncbi.nlm.nih.gov/pubmed/20046518 http://dx.doi.org/10.3349/ymj.2010.51.1.82

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