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A Small-Molecule Inhibitor of T. gondii Motility Induces the Posttranslational Modification of Myosin Light Chain-1 and Inhibits Myosin Motor Activity
Toxoplasma gondii is an obligate intracellular parasite that enters cells by a process of active penetration. Host cell penetration and parasite motility are driven by a myosin motor complex consisting of four known proteins: TgMyoA, an unconventional Class XIV myosin; TgMLC1, a myosin light chain;...
Autores principales: | Heaslip, Aoife T., Leung, Jacqueline M., Carey, Kimberly L., Catti, Federica, Warshaw, David M., Westwood, Nicholas J., Ballif, Bryan A., Ward, Gary E. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2800044/ https://www.ncbi.nlm.nih.gov/pubmed/20084115 http://dx.doi.org/10.1371/journal.ppat.1000720 |
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