A History of Alcohol Dependence Increases the Incidence and Severity of Postoperative Cognitive Dysfunction in Cardiac Surgical Patients

Postoperative cognitive dysfunction (POCD) commonly occurs after cardiac surgery. We tested the hypothesis that a history of alcohol dependence is associated with an increased incidence and severity of POCD in male patients undergoing cardiac surgery using cardiopulmonary bypass. Recent verbal and n...

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Autores principales: Hudetz, Judith A., Patterson, Kathleen M., Byrne, Alison J., Iqbal, Zafar, Gandhi, Sweeta D., Warltier, David C., Pagel, Paul S.
Formato: Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2800057/
https://www.ncbi.nlm.nih.gov/pubmed/20049218
http://dx.doi.org/10.3390/ijerph6112725
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author Hudetz, Judith A.
Patterson, Kathleen M.
Byrne, Alison J.
Iqbal, Zafar
Gandhi, Sweeta D.
Warltier, David C.
Pagel, Paul S.
author_facet Hudetz, Judith A.
Patterson, Kathleen M.
Byrne, Alison J.
Iqbal, Zafar
Gandhi, Sweeta D.
Warltier, David C.
Pagel, Paul S.
author_sort Hudetz, Judith A.
collection PubMed
description Postoperative cognitive dysfunction (POCD) commonly occurs after cardiac surgery. We tested the hypothesis that a history of alcohol dependence is associated with an increased incidence and severity of POCD in male patients undergoing cardiac surgery using cardiopulmonary bypass. Recent verbal and nonverbal memory and executive functions were assessed before and one week after surgery in patients with or without a history of alcohol dependence. Cognitive function was significantly reduced after cardiac surgery in patients with versus without a history of alcohol dependence. The results suggest that a history of alcohol dependence increases the incidence and severity of POCD after cardiac surgery.
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spelling pubmed-28000572010-01-04 A History of Alcohol Dependence Increases the Incidence and Severity of Postoperative Cognitive Dysfunction in Cardiac Surgical Patients Hudetz, Judith A. Patterson, Kathleen M. Byrne, Alison J. Iqbal, Zafar Gandhi, Sweeta D. Warltier, David C. Pagel, Paul S. Int J Environ Res Public Health Article Postoperative cognitive dysfunction (POCD) commonly occurs after cardiac surgery. We tested the hypothesis that a history of alcohol dependence is associated with an increased incidence and severity of POCD in male patients undergoing cardiac surgery using cardiopulmonary bypass. Recent verbal and nonverbal memory and executive functions were assessed before and one week after surgery in patients with or without a history of alcohol dependence. Cognitive function was significantly reduced after cardiac surgery in patients with versus without a history of alcohol dependence. The results suggest that a history of alcohol dependence increases the incidence and severity of POCD after cardiac surgery. Molecular Diversity Preservation International (MDPI) 2009-11 2009-10-27 /pmc/articles/PMC2800057/ /pubmed/20049218 http://dx.doi.org/10.3390/ijerph6112725 Text en © 2009 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0 This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Hudetz, Judith A.
Patterson, Kathleen M.
Byrne, Alison J.
Iqbal, Zafar
Gandhi, Sweeta D.
Warltier, David C.
Pagel, Paul S.
A History of Alcohol Dependence Increases the Incidence and Severity of Postoperative Cognitive Dysfunction in Cardiac Surgical Patients
title A History of Alcohol Dependence Increases the Incidence and Severity of Postoperative Cognitive Dysfunction in Cardiac Surgical Patients
title_full A History of Alcohol Dependence Increases the Incidence and Severity of Postoperative Cognitive Dysfunction in Cardiac Surgical Patients
title_fullStr A History of Alcohol Dependence Increases the Incidence and Severity of Postoperative Cognitive Dysfunction in Cardiac Surgical Patients
title_full_unstemmed A History of Alcohol Dependence Increases the Incidence and Severity of Postoperative Cognitive Dysfunction in Cardiac Surgical Patients
title_short A History of Alcohol Dependence Increases the Incidence and Severity of Postoperative Cognitive Dysfunction in Cardiac Surgical Patients
title_sort history of alcohol dependence increases the incidence and severity of postoperative cognitive dysfunction in cardiac surgical patients
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2800057/
https://www.ncbi.nlm.nih.gov/pubmed/20049218
http://dx.doi.org/10.3390/ijerph6112725
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