Cargando…
The mitochondrial genomes of sponges provide evidence for multiple invasions by Repetitive Hairpin-forming Elements (RHE)
BACKGROUND: The mitochondrial (mt) genomes of sponges possess a variety of features, which appear to be intermediate between those of Eumetazoa and non-metazoan opisthokonts. Among these features is the presence of long intergenic regions, which are common in other eukaryotes, but generally absent i...
Autores principales: | , , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2800124/ https://www.ncbi.nlm.nih.gov/pubmed/20003196 http://dx.doi.org/10.1186/1471-2164-10-591 |
_version_ | 1782175842683584512 |
---|---|
author | Erpenbeck, Dirk Voigt, Oliver Wörheide, Gert Lavrov, Dennis V |
author_facet | Erpenbeck, Dirk Voigt, Oliver Wörheide, Gert Lavrov, Dennis V |
author_sort | Erpenbeck, Dirk |
collection | PubMed |
description | BACKGROUND: The mitochondrial (mt) genomes of sponges possess a variety of features, which appear to be intermediate between those of Eumetazoa and non-metazoan opisthokonts. Among these features is the presence of long intergenic regions, which are common in other eukaryotes, but generally absent in Eumetazoa. Here we analyse poriferan mitochondrial intergenic regions, paying particular attention to repetitive sequences within them. In this context we introduce the mitochondrial genome of Ircinia strobilina (Lamarck, 1816; Demospongiae: Dictyoceratida) and compare it with mtDNA of other sponges. RESULTS: Mt genomes of dictyoceratid sponges are identical in gene order and content but display major differences in size and organization of intergenic regions. An even higher degree of diversity in the structure of intergenic regions was found among different orders of demosponges. One interesting observation made from such comparisons was of what appears to be recurrent invasions of sponge mitochondrial genomes by repetitive hairpin-forming elements, which cause large genome size differences even among closely related taxa. These repetitive hairpin-forming elements are structurally and compositionally divergent and display a scattered distribution throughout various groups of demosponges. CONCLUSION: Large intergenic regions of poriferan mt genomes are targets for insertions of repetitive hairpin- forming elements, similar to the ones found in non-metazoan opisthokonts. Such elements were likely present in some lineages early in animal mitochondrial genome evolution but were subsequently lost during the reduction of intergenic regions, which occurred in the Eumetazoa lineage after the split of Porifera. Porifera acquired their elements in several independent events. Patterns of their intra-genomic dispersal can be seen in the mt genome of Vaceletia sp. |
format | Text |
id | pubmed-2800124 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2009 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-28001242009-12-31 The mitochondrial genomes of sponges provide evidence for multiple invasions by Repetitive Hairpin-forming Elements (RHE) Erpenbeck, Dirk Voigt, Oliver Wörheide, Gert Lavrov, Dennis V BMC Genomics Research article BACKGROUND: The mitochondrial (mt) genomes of sponges possess a variety of features, which appear to be intermediate between those of Eumetazoa and non-metazoan opisthokonts. Among these features is the presence of long intergenic regions, which are common in other eukaryotes, but generally absent in Eumetazoa. Here we analyse poriferan mitochondrial intergenic regions, paying particular attention to repetitive sequences within them. In this context we introduce the mitochondrial genome of Ircinia strobilina (Lamarck, 1816; Demospongiae: Dictyoceratida) and compare it with mtDNA of other sponges. RESULTS: Mt genomes of dictyoceratid sponges are identical in gene order and content but display major differences in size and organization of intergenic regions. An even higher degree of diversity in the structure of intergenic regions was found among different orders of demosponges. One interesting observation made from such comparisons was of what appears to be recurrent invasions of sponge mitochondrial genomes by repetitive hairpin-forming elements, which cause large genome size differences even among closely related taxa. These repetitive hairpin-forming elements are structurally and compositionally divergent and display a scattered distribution throughout various groups of demosponges. CONCLUSION: Large intergenic regions of poriferan mt genomes are targets for insertions of repetitive hairpin- forming elements, similar to the ones found in non-metazoan opisthokonts. Such elements were likely present in some lineages early in animal mitochondrial genome evolution but were subsequently lost during the reduction of intergenic regions, which occurred in the Eumetazoa lineage after the split of Porifera. Porifera acquired their elements in several independent events. Patterns of their intra-genomic dispersal can be seen in the mt genome of Vaceletia sp. BioMed Central 2009-12-09 /pmc/articles/PMC2800124/ /pubmed/20003196 http://dx.doi.org/10.1186/1471-2164-10-591 Text en Copyright ©2009 Erpenbeck et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research article Erpenbeck, Dirk Voigt, Oliver Wörheide, Gert Lavrov, Dennis V The mitochondrial genomes of sponges provide evidence for multiple invasions by Repetitive Hairpin-forming Elements (RHE) |
title | The mitochondrial genomes of sponges provide evidence for multiple invasions by Repetitive Hairpin-forming Elements (RHE) |
title_full | The mitochondrial genomes of sponges provide evidence for multiple invasions by Repetitive Hairpin-forming Elements (RHE) |
title_fullStr | The mitochondrial genomes of sponges provide evidence for multiple invasions by Repetitive Hairpin-forming Elements (RHE) |
title_full_unstemmed | The mitochondrial genomes of sponges provide evidence for multiple invasions by Repetitive Hairpin-forming Elements (RHE) |
title_short | The mitochondrial genomes of sponges provide evidence for multiple invasions by Repetitive Hairpin-forming Elements (RHE) |
title_sort | mitochondrial genomes of sponges provide evidence for multiple invasions by repetitive hairpin-forming elements (rhe) |
topic | Research article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2800124/ https://www.ncbi.nlm.nih.gov/pubmed/20003196 http://dx.doi.org/10.1186/1471-2164-10-591 |
work_keys_str_mv | AT erpenbeckdirk themitochondrialgenomesofspongesprovideevidenceformultipleinvasionsbyrepetitivehairpinformingelementsrhe AT voigtoliver themitochondrialgenomesofspongesprovideevidenceformultipleinvasionsbyrepetitivehairpinformingelementsrhe AT worheidegert themitochondrialgenomesofspongesprovideevidenceformultipleinvasionsbyrepetitivehairpinformingelementsrhe AT lavrovdennisv themitochondrialgenomesofspongesprovideevidenceformultipleinvasionsbyrepetitivehairpinformingelementsrhe AT erpenbeckdirk mitochondrialgenomesofspongesprovideevidenceformultipleinvasionsbyrepetitivehairpinformingelementsrhe AT voigtoliver mitochondrialgenomesofspongesprovideevidenceformultipleinvasionsbyrepetitivehairpinformingelementsrhe AT worheidegert mitochondrialgenomesofspongesprovideevidenceformultipleinvasionsbyrepetitivehairpinformingelementsrhe AT lavrovdennisv mitochondrialgenomesofspongesprovideevidenceformultipleinvasionsbyrepetitivehairpinformingelementsrhe |