Cargando…
Energetic signatures of single base bulges: thermodynamic consequences and biological implications
DNA bulges are biologically consequential defects that can arise from template-primer misalignments during replication and pose challenges to the cellular DNA repair machinery. Calorimetric and spectroscopic characterizations of defect-containing duplexes reveal systematic patterns of sequence-conte...
Autores principales: | , , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2800203/ https://www.ncbi.nlm.nih.gov/pubmed/19946018 http://dx.doi.org/10.1093/nar/gkp1036 |