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Energetic signatures of single base bulges: thermodynamic consequences and biological implications

DNA bulges are biologically consequential defects that can arise from template-primer misalignments during replication and pose challenges to the cellular DNA repair machinery. Calorimetric and spectroscopic characterizations of defect-containing duplexes reveal systematic patterns of sequence-conte...

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Detalles Bibliográficos
Autores principales:	Minetti, Conceição A. S. A., Remeta, David P., Dickstein, Rian, Breslauer, Kenneth J.
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2010
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2800203/ https://www.ncbi.nlm.nih.gov/pubmed/19946018 http://dx.doi.org/10.1093/nar/gkp1036

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