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The RNA polymerase activity of SARS-coronavirus nsp12 is primer dependent

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An RNA-dependent RNA polymerase (RdRp) is the central catalytic subunit of the RNA-synthesizing machinery of all positive-strand RNA viruses. Usually, RdRp domains are readily identifiable by comparative sequence analysis, but biochemical confirmation and characterization can be hampered by intrinsi...

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Detalles Bibliográficos
Autores principales:	te Velthuis, Aartjan J. W., Arnold, Jamie J., Cameron, Craig E., van den Worm, Sjoerd H. E., Snijder, Eric J.
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2010
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2800238/ https://www.ncbi.nlm.nih.gov/pubmed/19875418 http://dx.doi.org/10.1093/nar/gkp904

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