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A luminal epithelial stem cell that is a cell of origin for prostate cancer

In epithelial tissues, the lineage relationship between normal progenitor cells and cell type(s) of origin for cancer has been poorly understood. Here we show that a known regulator of prostate epithelial differentiation, the homeobox gene Nkx3.1, marks a stem cell population that functions during p...

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Detalles Bibliográficos
Autores principales:	Wang, Xi, Kruithof-de Julio, Marianna, Economides, Kyriakos D., Walker, David, Yu, Hailong, Halili, M. Vivienne, Hu, Ya-Ping, Price, Sandy M., Abate-Shen, Cory, Shen, Michael M.
Formato:	Texto
Lenguaje:	English
Publicado:	2009
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2800362/ https://www.ncbi.nlm.nih.gov/pubmed/19741607 http://dx.doi.org/10.1038/nature08361

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