Cargando…
Effects of mosapride on motility of the small intestine and caecum in normal horses after jejunocaecostomy
The purpose of the present study was to evaluate the prokinetic effects of mosapride with non-invasive assessment of myoelectrical activity in the small intestine and caecum of healthy horses after jejunocaecostomy. Six horses underwent celiotomy and jejunocaecostomy, and were treated with mosapride...
Autores principales: | , , , , , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Korean Society of Veterinary Science
2009
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2801111/ https://www.ncbi.nlm.nih.gov/pubmed/19461212 http://dx.doi.org/10.4142/jvs.2009.10.2.157 |
_version_ | 1782175902546788352 |
---|---|
author | Okamura, Kouichi Sasaki, Naoki Kikuchi, Takuya Murata, Aya Lee, Inhyung Yamada, Haruo Inokuma, Hisashi |
author_facet | Okamura, Kouichi Sasaki, Naoki Kikuchi, Takuya Murata, Aya Lee, Inhyung Yamada, Haruo Inokuma, Hisashi |
author_sort | Okamura, Kouichi |
collection | PubMed |
description | The purpose of the present study was to evaluate the prokinetic effects of mosapride with non-invasive assessment of myoelectrical activity in the small intestine and caecum of healthy horses after jejunocaecostomy. Six horses underwent celiotomy and jejunocaecostomy, and were treated with mosapride (treated group) at 1.5 mg/kg per osos once daily for 5 days after surgery. The other six horses did not receive treatment and were used as controls (non-treated group). The electrointestinography (EIG) maximum amplitude was used to measure intestinal motility. Motility significantly decreased following surgery. In the treated group, the EIG maximum amplitude of the small intestine was significantly higher than in the controls from day 6~31 after treatment. These findings clearly indicate that mosapride could overcome the decline of intestinal motility after jejunocaecostomy in normal horses. |
format | Text |
id | pubmed-2801111 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2009 |
publisher | The Korean Society of Veterinary Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-28011112010-01-11 Effects of mosapride on motility of the small intestine and caecum in normal horses after jejunocaecostomy Okamura, Kouichi Sasaki, Naoki Kikuchi, Takuya Murata, Aya Lee, Inhyung Yamada, Haruo Inokuma, Hisashi J Vet Sci Original Article The purpose of the present study was to evaluate the prokinetic effects of mosapride with non-invasive assessment of myoelectrical activity in the small intestine and caecum of healthy horses after jejunocaecostomy. Six horses underwent celiotomy and jejunocaecostomy, and were treated with mosapride (treated group) at 1.5 mg/kg per osos once daily for 5 days after surgery. The other six horses did not receive treatment and were used as controls (non-treated group). The electrointestinography (EIG) maximum amplitude was used to measure intestinal motility. Motility significantly decreased following surgery. In the treated group, the EIG maximum amplitude of the small intestine was significantly higher than in the controls from day 6~31 after treatment. These findings clearly indicate that mosapride could overcome the decline of intestinal motility after jejunocaecostomy in normal horses. The Korean Society of Veterinary Science 2009-06 2009-06-11 /pmc/articles/PMC2801111/ /pubmed/19461212 http://dx.doi.org/10.4142/jvs.2009.10.2.157 Text en Copyright © 2009 The Korean Society of Veterinary Science https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0 (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Okamura, Kouichi Sasaki, Naoki Kikuchi, Takuya Murata, Aya Lee, Inhyung Yamada, Haruo Inokuma, Hisashi Effects of mosapride on motility of the small intestine and caecum in normal horses after jejunocaecostomy |
title | Effects of mosapride on motility of the small intestine and caecum in normal horses after jejunocaecostomy |
title_full | Effects of mosapride on motility of the small intestine and caecum in normal horses after jejunocaecostomy |
title_fullStr | Effects of mosapride on motility of the small intestine and caecum in normal horses after jejunocaecostomy |
title_full_unstemmed | Effects of mosapride on motility of the small intestine and caecum in normal horses after jejunocaecostomy |
title_short | Effects of mosapride on motility of the small intestine and caecum in normal horses after jejunocaecostomy |
title_sort | effects of mosapride on motility of the small intestine and caecum in normal horses after jejunocaecostomy |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2801111/ https://www.ncbi.nlm.nih.gov/pubmed/19461212 http://dx.doi.org/10.4142/jvs.2009.10.2.157 |
work_keys_str_mv | AT okamurakouichi effectsofmosaprideonmotilityofthesmallintestineandcaecuminnormalhorsesafterjejunocaecostomy AT sasakinaoki effectsofmosaprideonmotilityofthesmallintestineandcaecuminnormalhorsesafterjejunocaecostomy AT kikuchitakuya effectsofmosaprideonmotilityofthesmallintestineandcaecuminnormalhorsesafterjejunocaecostomy AT murataaya effectsofmosaprideonmotilityofthesmallintestineandcaecuminnormalhorsesafterjejunocaecostomy AT leeinhyung effectsofmosaprideonmotilityofthesmallintestineandcaecuminnormalhorsesafterjejunocaecostomy AT yamadaharuo effectsofmosaprideonmotilityofthesmallintestineandcaecuminnormalhorsesafterjejunocaecostomy AT inokumahisashi effectsofmosaprideonmotilityofthesmallintestineandcaecuminnormalhorsesafterjejunocaecostomy |