A Novel Approach Using DNA-Repair–Deficient Chicken DT40 Cell Lines for Screening and Characterizing the Genotoxicity of Environmental Contaminants

BACKGROUND: Many bacterial or mammalian cell-based test systems, such as the Ames test, chromosomal aberration assays, or gene mutation assays, are commonly used in developed countries to detect the genotoxicity of industrial chemicals. However, the specificity is generally limited and the sensitivi...

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Detalles Bibliográficos
Autores principales: Ji, Kyunghee, Kogame, Toshiaki, Choi, Kyungho, Wang, Xin, Lee, Jinyoung, Taniguchi, Yoshihito, Takeda, Shunichi
Formato: Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2801191/
https://www.ncbi.nlm.nih.gov/pubmed/20049126
http://dx.doi.org/10.1289/ehp.0900842

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